| Primary Identifier | MGI:1344363 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 23806 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable enzyme binding activity; ubiquitin protein ligase activity; and zinc ion binding activity. Acts upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be located in Lewy body and nuclear body. Predicted to be part of Cul3-RING ubiquitin ligase complex; Cul4A-RING E3 ubiquitin ligase complex; and SCF ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Is expressed in hippocampus. Orthologous to human ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1). PHENOTYPE: Mice homozygous for a conditional allele activated in myeloid cells exhibit increased susceptibility to Herpesvirales infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
