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Protein Coding Gene : Kcnk13 potassium channel, subfamily K, member 13

Primary Identifier  MGI:2384976 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  217826
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to act upstream of or within monoatomic ion transmembrane transport and potassium ion transport. Predicted to be located in membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Is expressed in dentate gyrus subgranular zone and heart. Orthologous to human KCNK13 (potassium two pore domain channel subfamily K member 13).
PHENOTYPE: Homozygous knockout reduces the surveillance activity of microglial cells in the brain. [provided by MGI curators]
  • synonyms:
  • Kcnk13,
  • LOC380778,
  • gene model 1685, (NCBI),
  • MGI:2686416,
  • LOC381712,
  • MGI:2145065,
  • F730021E22Rik,
  • expressed sequence BB085247,
  • RIKEN cDNA F730021E22 gene,
  • potassium channel, subfamily K, member 13,
  • Gm1685,
  • BB085247,
  • MGI:2686531,
  • THIK-1,
  • Gm1570,
  • gene model 1570, (NCBI)

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Genome

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0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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