Primary Identifier | MGI:3664773 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Nodal |
Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A construct consisting of a floxed PGK-hygro cassette, wild-type exons 2 and 3, a third loxP site, and a mutant exon 2 and 3 cDNA resistant to subtilisin-like proprotein convertase cleavage due to removal of the cleavage motif. Cre-mediated recombination results in production of a cleavage resistant protein. |