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Allele : Nodal<tm1Dbc> nodal growth differentiation factor; targeted mutation 1, Daniel B Constam

Primary Identifier  MGI:3664773 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Nodal
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  A construct consisting of a floxed PGK-hygro cassette, wild-type exons 2 and 3, a third loxP site, and a mutant exon 2 and 3 cDNA resistant to subtilisin-like proprotein convertase cleavage due to removal of the cleavage motif. Cre-mediated recombination results in production of a cleavage resistant protein.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele