| Primary Identifier | MGI:7434618 | Allele Type | Endonuclease-mediated |
| Gene | F2rl1 | Strain of Origin | C57BL/6N |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Lysine codon 36 (AAA) in exon 2 was changed to aspartic acid (GAA) (p.K36E) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation results in the resistance of the encoded peptide to skin-expressed serine proteases while remaining sensitive to cleavage by F10. |
