| First Author | Mantani A | Year | 1998 |
| Journal | Gene | Volume | 222 |
| Issue | 2 | Pages | 229-35 |
| PubMed ID | 9831657 | Mgi Jnum | J:51406 |
| Mgi Id | MGI:1316587 | Doi | 10.1016/s0378-1119(98)00488-0 |
| Citation | Mantani A, et al. (1998) The mouse Id2 and Id4 genes: structural organization and chromosomal localization. Gene 222(2):229-35 |
| abstractText | The Id proteins belong to a family of nuclear HLH proteins lacking a basic region and thought to function as dominant-negative regulators of bHLH proteins during cell growth and differentiation. In this paper, we report the genomic organization of the mouse Id2 and Id4 genes. These genes each span approximately 3 kb of the mouse genome and are each organized as three exons with recognizable splice donor and acceptor consensus sequences. Their genomic organization is very similar, consistent with their having evolved from a common, ancestral Id-like gene. Using FISH analysis, we have localized the mouse Id2 and Id4 genes to mouse chromosome 12 and 13, respectively. |
