Primary Identifier | MGI:6259531 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tut4 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129P2/OlaHsd)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 15 was replaced with a modified one in which the codons for Asp1026 and Asp1028 were mutated to encode alanine. These mutations result in an enzymatically inactive protein. Flp-mediated recombination removed the selection cassette inserted downstream of the modified exon 15. |