Primary Identifier | IPR003381 | Type | Family |
Short Name | L4 |
description | The late 100kDa protein (also known as L4) inhibits host translation while promoting late viral translation by ribosome shunting []. It blocks host cap-dependent translation by binding to eIF4G, displacing MKNK1 from cap initiation complexes and preventing EIF4E phosphorylation []. |