First Author | Matsugi T | Year | 1990 |
Journal | Mol Cell Biol | Volume | 10 |
Issue | 3 | Pages | 1259-64 |
PubMed ID | 2106070 | Mgi Jnum | J:156086 |
Mgi Id | MGI:4418648 | Doi | 10.1128/mcb.10.3.1259 |
Citation | Matsugi T, et al. (1990) Identification, nuclear localization, and DNA-binding activity of the zinc finger protein encoded by the Evi-1 myeloid transforming gene. Mol Cell Biol 10(3):1259-64 |
abstractText | Activation of the Evi-1 zinc finger gene is a common event associated with transformation of murine myeloid leukemias. To characterize the gene product, we developed antisera against various protein domains. These antisera primarily detected a 145-kilodalton nuclear protein that bound double-stranded DNA. Binding was inhibited by chelating agents and partially restored by zinc ions. |