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Publication : Identification, nuclear localization, and DNA-binding activity of the zinc finger protein encoded by the Evi-1 myeloid transforming gene.

First Author  Matsugi T Year  1990
Journal  Mol Cell Biol Volume  10
Issue  3 Pages  1259-64
PubMed ID  2106070 Mgi Jnum  J:156086
Mgi Id  MGI:4418648 Doi  10.1128/mcb.10.3.1259
Citation  Matsugi T, et al. (1990) Identification, nuclear localization, and DNA-binding activity of the zinc finger protein encoded by the Evi-1 myeloid transforming gene. Mol Cell Biol 10(3):1259-64
abstractText  Activation of the Evi-1 zinc finger gene is a common event associated with transformation of murine myeloid leukemias. To characterize the gene product, we developed antisera against various protein domains. These antisera primarily detected a 145-kilodalton nuclear protein that bound double-stranded DNA. Binding was inhibited by chelating agents and partially restored by zinc ions.
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