| Primary Identifier | MGI:96394 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 15896 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable integrin binding activity. Predicted to be involved in cell adhesion. Located in microvillus; plasma membrane; and uropod. Is expressed in central nervous system; extraembryonic component; female reproductive system; retina; and vascular element. Orthologous to human ICAM2 (intercellular adhesion molecule 2). PHENOTYPE: Homozygous inactivation of this gene results in increased respiratory responsiveness due to an increased accumulation of eosinophils in the lung interstitium and a concomittant delay in the increase of eosinophils in the airway lumen during the development of an allergic inflammatory response. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
