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Protein Coding Gene : Secisbp2 SECIS binding protein 2

Primary Identifier  MGI:1922670 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  75420
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ribonucleoprotein complex binding activity and selenocysteine insertion sequence binding activity. Acts upstream of or within forebrain development and regulation of gene expression. Located in mitochondrion. Part of ribonucleoprotein complex. Is expressed in cerebellum; retina inner nuclear layer; and retina outer nuclear layer. Human ortholog(s) of this gene implicated in thyroid gland disease. Orthologous to human SECISBP2 (SECIS binding protein 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete preweaning lethality while heterozygotes exhibit reduced serum selenium levels. [provided by MGI curators]
  • synonyms:
  • MGI:1919610,
  • SBP2,
  • Secisbp2,
  • RIKEN cDNA 2210413N07 gene,
  • RIKEN cDNA 2810012K13 gene,
  • 2210413N07Rik,
  • 2810012K13Rik,
  • SECIS binding protein 2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For