| Primary Identifier | MGI:95405 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 13849 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables oxysterol binding activity. Acts upstream of or within response to organic cyclic compound. Predicted to be located in intracellular membrane-bounded organelle and membrane. Is expressed in several structures, including brain ventricle and choroid plexus; exocrine system; integumental system; nervous system; and nose. Human ortholog(s) of this gene implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Orthologous to human EPHX1 (epoxide hydrolase 1). PHENOTYPE: Mice homozygous for a knock-out allele are highly resistant to DMBA-induced skin carcinogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
