Primary Identifier | IPR039545 | Type | Family |
Short Name | PGAP2 |
description | PGAP2, also known as FRAG1, is involved in the lipid remodeling steps of glycosylphosphatidylinositol (GPI)-anchor maturation []. Immediately after attachment of GPI to newly synthesized proteins, inositol-linked palmitate is removed by deacylase PGAP1 in the ER. The inositol-deacylation is essential for subsequent steps in fatty acid remodeling in the Golgi. PGAP3 removes an unsaturated fatty chain at sn-2 and PGAP2 reacylation of sn-2 with stearic acid follows []. |