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Allele : Tyr<em2Kest> tyrosinase; endonuclease-mediated mutation 2, Robert A Kesterson

Primary Identifier  MGI:6159170 Allele Type  Endonuclease-mediated
Attribute String  Hypomorph Gene  Tyr
Strain of Origin  (B6(Cg)-Tyr<c-2J> x C57BL/6J)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 mediated mutagenesis created a 15 bp in-frame deletion in a region proximal to the 5' end of exon 1 resulting in a 5 amino acid deletion (GPQFPFKGVDDRESW to GPQLDDRESW) and a 3 bp in-frame deletion resulting in a loss of threonine at position 244.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • chandana,
  • chandana
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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2 Publication categories

Trail: Allele