| Primary Identifier | MGI:1856924 | Allele Type | Spontaneous |
| Gene | Utp14b | Inheritance Mode | Recessive |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| description | Homozygous females are normal and fertile. Homozygous males have small testes, normal serum testosterone, elevated serum follicle-stimulating hormone, azoospermia, and normal body and seminal vesicle weights. At 3 to 4 weeks, there is a reduction in number of spermatogenic cells that proceeds at different rates in different tubules, but by 8 to 10 weeks most tubules are devoid of germ cells, leaving only Sertoli cells(J:9278). |
| molecularNote | A CC to GAAAAG substitution 304 bp from the ATG putatively results in a frame shift such that after the first 105 amino acids, there are two substitutions (GE to LF) followed by a stop codon. |
