Primary Identifier | MGI:6294491 | Allele Type | Transgenic |
Attribute String | Epitope tag, Inducible, Inserted expressed sequence | Gene | Tg(Myh6*/tetO-Hspb8*K141N)#Atsa |
Strain of Origin | Not Specified | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The coding region of mouse heat shock protein 8 with the lysine to asparagine missense mutation at amino acid 141 (K141N) with an N-terminal HA tag was inserted into an MHCminTetO-promotor construct. The expression of the construct was driven by a mouse alpha-myosin heavy chain promoter with 3 altered GATA sites and 2 altered thyroid-like response elements for maintaining low levels of cardiac-specific expression, under the control of a tetracycline operator. |