| Primary Identifier | IPR029700 | Type | Family |
| Short Name | GEMC1 |
| description | Geminin coiled-coil domain-containing protein 1 (GEMC1) is a regulator of DNA replication. It promotes initiation of chromosomal DNA replication by mediating TopBP1- and cdk2-dependent recruitment of cdc45 onto replication origins []. GEMC1 contains a region similar to the coiled-coil domain of geminin, an essential vertebrate replication protein. However, only some of the amino acid residues critical for geminin function are conserved in GEMC1 []. |
