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Protein Coding Gene : Cdh11 cadherin 11

Primary Identifier  MGI:99217 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  12552
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable beta-catenin binding activity and cadherin binding activity. Involved in modulation of chemical synaptic transmission. Acts upstream of or within corticospinal tract morphogenesis. Located in cytoplasm and plasma membrane. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Elsahy-Waters syndrome and Teebi hypertelorism syndrome 2. Orthologous to human CDH11 (cadherin 11).
PHENOTYPE: Homozygous mutant animals appear healthy and fertile. [provided by MGI curators]
  • synonyms:
  • cadherin 11,
  • osteoblast-cadherin,
  • Cad11,
  • Cdh11,
  • MGD-MRK-15974,
  • OB-cadherin

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

2 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For