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Publication : Chromosomal mapping of five mouse G protein gamma subunits.

First Author  Downes GB Year  1999
Journal  Genomics Volume  57
Issue  1 Pages  173-6
PubMed ID  10191100 Mgi Jnum  J:54663
Mgi Id  MGI:1335680 Doi  10.1006/geno.1999.5763
Citation  Downes GB, et al. (1999) Chromosomal mapping of five mouse G protein gamma subunits. Genomics 57(1):173-6
abstractText  Heterotrimeric G proteins, composed of alpha, beta, and gamma subunits, transduce signals from transmembrane receptors to a wide range of intracellular effecters. The G protein gamma subunits, which play an indispensible role in this communication, constitute a large and diverse multigene family. Using an interspecific back cross panel, we have determined the mouse chromosomal locations of five gamma subunit genes: gamma 2, gamma 8, gamma 10, gamma 12, and gamma Cone. Combined with previous mapping studies, these data indicate that, with the possible exception of gamma 1 and gamma 11, the G protein gamma subunit genes are well dispersed within the mouse and human genomes. (C) 1999 Academic Press.
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