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Protein Coding Gene : Gper1 G protein-coupled estrogen receptor 1

Primary Identifier  MGI:1924104 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  76854
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables nuclear estrogen receptor activity. Involved in several processes, including cellular response to estradiol stimulus; positive regulation of cell communication; and positive regulation of macromolecule metabolic process. Located in cytoplasm and plasma membrane. Is active in hippocampal mossy fiber to CA3 synapse. Is expressed in embryo; metanephros; pituitary gland; stomach glandular region epithelium; and stomach glandular region gastric gland. Orthologous to human GPER1 (G protein-coupled estrogen receptor 1).
PHENOTYPE: Mice homozygous for a knockout allele exhibit decreased thymic atrophy, insulin, and glucagon responses following treatment with PGE2. [provided by MGI curators]
  • synonyms:
  • 6330420K13Rik,
  • Gper,
  • CMKRL2,
  • RIKEN cDNA 6330420K13 gene,
  • constitutively expressed peptide-like receptor like,
  • MGI:109381,
  • GPCR-Br,
  • MGD-MRK-38426,
  • FEG-1,
  • Gpr30,
  • Gper1,
  • G protein-coupled receptor 30,
  • G protein-coupled estrogen receptor 1,
  • Ceprl

Features --> Cross References

Genome

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0 CDSs

0 Exons

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

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Expression

Gene --> Expression annotations

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Disease

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Literature

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1 Driver For