| Primary Identifier | MGI:88111 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 381290 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables scaffold protein binding activity and sodium channel regulator activity. Involved in several processes, including negative regulation of blood vessel endothelial cell migration; negative regulation of calcineurin-NFAT signaling cascade; and negative regulation of cardiac muscle hypertrophy in response to stress. Located in T-tubule and sperm flagellum. Part of protein-containing complex. Is expressed in several structures, including bladder; heart; intestine wall; liver; and nervous system. Orthologous to human ATP2B4 (ATPase plasma membrane Ca2+ transporting 4). PHENOTYPE: Homozygous null mice display male infertility with impaired sperm motility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
