| Primary Identifier | MGI:1889273 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 56188 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables sodium channel regulator activity. Involved in positive regulation of sodium ion export across plasma membrane and regulation of cardiac muscle cell membrane potential. Located in sarcolemma. Is expressed in several structures, including central nervous system; genitourinary system; liver; lung; and retina. Orthologous to human FXYD1 (FXYD domain containing ion transport regulator 1). PHENOTYPE: Adult mice homozygous for a knock-out allele exhibit cardiac hypertrophy, increased ejection fraction, and a 50% reduction in total Na-K-ATPase activity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
