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Protein Coding Gene : Tcfl5 transcription factor-like 5 (basic helix-loop-helix)

Primary Identifier  MGI:2672878 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  277353
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Located in male germ cell nucleus. Is expressed in brain and testis. Orthologous to human TCFL5 (transcription factor like 5).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit male sterility associated with small testis size, azoospermia, multinucleated giant male germ cells, arrest of male meiosis in a diplotene like stage, and increased male germ cell apoptosis. [provided by MGI curators]
  • synonyms:
  • AV260129,
  • Tcfl5,
  • transcription factor-like 5 (basic helix-loop-helix),
  • MGI:2139262,
  • FIG beta,
  • expressed sequence AV260129,
  • Figlb

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Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

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Function

Mouse features --> Functions (GO terms)

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