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Protein Domain : Transcription termination factor CPSF1, archaea

Primary Identifier  IPR019975 Type  Family
Short Name  aCPSF1
description  The general transcription termination factor CPSF1 is ubiquitously distributed among Archaea (aCPSF1). It was recently characterised as a ribonuclease essential for transcription termination to ensure programmed transcriptome and an optimal growth and physiology. It associates with archaeal RNAP and cleaves the transcript at the 3'-end, downstream the uridine-rich sequences recognised by its N-terminal KH-domain, a characteristic RNA binding domain [, ].

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