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Protein Coding Gene : Ddx21 DExD box helicase 21

Primary Identifier  MGI:1860494 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  56200
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables double-stranded RNA binding activity and identical protein binding activity. Involved in positive regulation of canonical NF-kappaB signal transduction and positive regulation of myeloid dendritic cell cytokine production. Acts upstream of or within response to exogenous dsRNA and response to virus. Located in cytosol. Is expressed in several structures, including 1st branchial arch; early conceptus; genitourinary system; and limb. Orthologous to human DDX21 (DExD-box helicase 21).
PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit embryonic lethality. [provided by MGI curators]
  • synonyms:
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 21,
  • MGI:2143708,
  • DNA segment, Chr 10, ERATO Doi 645, expressed,
  • MGD-MRK-34073,
  • RH-II/Gualpha,
  • MGI:2143543,
  • AI255159,
  • expressed sequence AI255159,
  • DNA segment, Chr 10, Wayne State University 42, expressed,
  • MGI:1277112,
  • expressed sequence AL022742,
  • D10Wsu42e,
  • MGI:106380,
  • D10Ertd645e,
  • Ddx21,
  • RH II/Gu,
  • DExD box helicase 21,
  • AL022742

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For