Primary Identifier | MGI:107532 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 16211 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables Hsp90 protein binding activity; importin-alpha family protein binding activity; and nuclear import signal receptor activity. Acts upstream of or within ribosomal protein import into nucleus. Located in cytoplasmic stress granule. Part of protein-containing complex. Is expressed in brain; gonad; liver; neural retina; and pancreas. Orthologous to human KPNB1 (karyopherin subunit beta 1). PHENOTYPE: Homozygous mutation of this gene results in lethality shortly after implantation. [provided by MGI curators] |