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Allele : Lmbr1<tm1Kng> limb region 1; targeted mutation 1, David M Kingsley

Primary Identifier  MGI:3579991 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lmbr1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A 1.1 kb sequence containing 365 bp upstream of the predicted translational start site of exon 1 and 696 bp downstream of the exon 1 splice donor site was replaced with a PGKneo selection cassette. The deleted sequence was common to both known transcripts. Northern blot of mutant brains suggested that the allele may not have been a null as overexposure to probes demonstrated transcripts at ~7% of wild-type levels.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Lmbr1<ATG>,
  • Lmbr1<ATG>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele