| Primary Identifier | MGI:6874619 | Allele Type | Targeted |
| Gene | Gpx4 | Transmission | Germline |
| Strain of Origin | (C57BL/6J x 129S6/SvEvTac)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 3 was replaced with a modified one in which a point mutation (UGA to UGC) results in the substitution of the catalytically active selenocysteine to a cysteine. A loxP-flanked neomycin resistance cassette was inserted downstream of exon 7. GPX4-specific activity is undetectable in homozygous tissues using PCOOH as substrate. |
