Primary Identifier | MGI:1197019 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 16538 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable delayed rectifier potassium channel activity and potassium channel regulator activity. Involved in potassium ion transport. Located in perinuclear region of cytoplasm and plasma membrane. Part of voltage-gated potassium channel complex. Orthologous to human KCNS1 (potassium voltage-gated channel modifier subfamily S member 1). PHENOTYPE: Mice homozygous for a conditional allele activated in DRG exhibit increased sensitivity to mechanical stimulation prior to and following neuropathic pain induction and cold nociception following neuropathic pain induction, and increased performance on a rotarod. [provided by MGI curators] |