| Type | MGI:General | Description | mice subjected to transverse aortic constriction (TAC) do not show an increase in cardiac pump function, with no increase in % fractional shortening of % ejection fraction as seen in wild-type mice mice show decreased TAC-induced hypertrophic responses, such as heart/bodyweight ratio, heart weight/tibia length ratio, myocyte size, and expression of hypertrophic markers indicating alleviation of TAC-induced cardiac hypertrophy mice show alleviation of TAC-induced increases in fibrotic area |
