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Allele : Htt<tm1(HTT)Arte> huntingtin; targeted mutation 1, TaconicArtemis
Primary Identifier  MGI:5426926 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Null/knockout Gene  Htt
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A cDNA construct carrying mutant human Huntington gene (145Q) truncated at position ~aa1000 (Difiglia site) under the control of CAGGS promoter was targeted into endogenous mouse Htt locus. Endogenous Htt gene expression was disrupted due to deletion of partial promoter region and exon 1.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

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0 Driven By

4 Publication categories

Trail: Allele




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