Primary Identifier | IPR035438 | Type | Family |
Short Name | SARA/endofin |
description | This group represents zinc finger FYVE domain-containing proteins SARA and endofin.SARA (also known as zinc finger FYVE domain-containing protein 9) is a component of the TGFbeta pathway that functions to recruit Smad2 to the TGFbeta receptor []. Endofin (zinc finger FYVE domain-containing protein 16) facilitates TGF-beta signaling by bringing Smad4 to the proximity of the receptor complex []. Both are involved in regulating membrane trafficking in the endosomal pathway [, ]. |