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Protein Domain : Zinc finger FYVE domain containing protein, SARA/endofin

Primary Identifier  IPR035438 Type  Family
Short Name  SARA/endofin
description  This group represents zinc finger FYVE domain-containing proteins SARA and endofin.SARA (also known as zinc finger FYVE domain-containing protein 9) is a component of the TGFbeta pathway that functions to recruit Smad2 to the TGFbeta receptor []. Endofin (zinc finger FYVE domain-containing protein 16) facilitates TGF-beta signaling by bringing Smad4 to the proximity of the receptor complex []. Both are involved in regulating membrane trafficking in the endosomal pathway [, ].

1 Child Features

0 Parent Features

6 Protein Domain Regions