Primary Identifier | MGI:2673998 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 233071 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables GTPase activator activity. Predicted to be involved in regulation of dendritic spine morphogenesis and small GTPase-mediated signal transduction. Predicted to act upstream of or within protein transport. Located in cytoplasm and plasma membrane. Is expressed in brain; parathyroid gland; peripheral nervous system; and prostate gland. Orthologous to human ARHGAP33 (Rho GTPase activating protein 33). PHENOTYPE: Mice homozygous for a null mutation display region specific thinning of the cerebral cortex with reduced dendritic complexity. [provided by MGI curators] |