First Author | Yamamoto I | Year | 2002 |
Journal | Biochim Biophys Acta | Volume | 1579 |
Issue | 2-3 | Pages | 185-8 |
PubMed ID | 12427554 | Mgi Jnum | J:80462 |
Mgi Id | MGI:2445897 | Doi | 10.1016/s0167-4781(02)00511-0 |
Citation | Yamamoto I, et al. (2002) cDNA cloning and mRNA expression of Transformer 2 (Tra 2) in chicken embryo. Biochim Biophys Acta 1579(2-3):185-8 |
abstractText | We report the cloning of a chicken Transformer 2 (Tra 2) cDNA that encodes a protein of 289 amino acids which are 97.9% identical to those of mammalian splicing factor, Tra 2. Tra 2 mRNA was expressed in chicken embryonic tissues and was observed as a band of 1.5 kb by Northern blot analysis. Whole mount in situ hybridization showed an mRNA expression of Tra 2 in telencephalon, mandible, hyoid arch, wing and leg buds as early as day 3.5 of incubation. These results suggest that the Tra 2 gene may play a role in organogenesis in the chicken embryo. |