| Primary Identifier | MGI:1345629 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 23912 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including actin filament organization; cell migration; and regulation of actin cytoskeleton organization. Predicted to be located in cytoplasm; cytoskeleton; and membrane. Predicted to be active in cytosol and plasma membrane. Orthologous to human RHOF (ras homolog family member F, filopodia associated). PHENOTYPE: Mice homozygous for a knock-out allele exhibit macrothrombocytopenia without an effect on filopodia generation. Homozygous knockout also leads to the reduction of the number of B cells in the spleen marginal zone. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
