| Primary Identifier | MGI:2183936 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Klf4 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 2.8 kb region of the gene encompassing part of exon 1, exon 2, and exon 3 was replaced with a PGK-neo cassette via homologous recombination. The targeted region encodes the translation initiation codon and the first of 3 zinc finger domains. Northern blot analysis and immunohistochemistry of skin sections from homozygous mutant animals verified the absence of gene expression. |
