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Protein Coding Gene : Klhl25 kelch-like 25

Primary Identifier  MGI:2668031 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  207952
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ubiquitin-like ligase-substrate adaptor activity. Involved in positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; positive regulation of fatty acid oxidation; and ubiquitin-dependent protein catabolic process. Part of Cul3-RING ubiquitin ligase complex. Is expressed in central nervous system; nervous system; peripheral nervous system; and retina. Orthologous to human KLHL25 (kelch like family member 25).
PHENOTYPE: Mice harboring an ENU-induced single point mutation show abnormally white teeth. [provided by MGI curators]
  • synonyms:
  • kelch-like 25,
  • MGI:1923803,
  • Klhl25,
  • 2810402K13Rik,
  • BC027373,
  • cDNA sequence BC027373,
  • RIKEN cDNA 2810402K13 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For