| Primary Identifier | MGI:1924363 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 77113 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable actin binding activity; protein homodimerization activity; and ubiquitin-like ligase-substrate adaptor activity. Involved in protein ubiquitination. Located in cytoplasm. Part of Cul3-RING ubiquitin ligase complex. Is expressed in white fat. Orthologous to human KLHL2 (kelch like family member 2). PHENOTYPE: Mice homozygous for null mutations are physically normal and do not exhibit hyperkalemia or metabolic acidosis, despite increased WNK4 protein levels in the kidney medulla. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
