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Allele : Crb1<rd8+em1Mvw> crumbs family member 1, photoreceptor morphogenesis associated; endonuclease-mediated revertant 1, Michael Wiles

Primary Identifier  MGI:5498686 Allele Type  Endonuclease-mediated
Gene  Crb1 Transmission  Germline
Strain of Origin  C57BL/6NJ Is Recombinase  false
Is Wild Type  false
molecularNote  TALEN targeting of exon 9 for homologous recombination with single stranded oligonucleotides (ssODNs) replaces the deleted nucleotide (C/G) in the retinal degeneration 8 (rd8) mutation and incorporates 5 synonymous base substitutions inside the TALEN binding regions.
  • mutations:
  • Insertion
  • synonyms:
  • Crb1<em1Mvw>,
  • corrected,
  • Crb1<cor>,
  • Crb1<cor>,
  • corrected,
  • Crb1<em1Mvw>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele