| Primary Identifier | IPR015056 | Type | Domain |
| Short Name | NRBF2_C |
| description | Nuclear receptor-binding factor 2 (NRBF2) plays an essential role in autophagy, the cellular pathway that degrades long-lived proteins and other cytoplasmic contents through lysosomes. NRBF2 binds Atg14L - a Beclin-binding protein - directly via the MIT domain and enhances Atg14L-linked Vps34 kinase (a class III phosphatidylinositol-3 kinase) activity and autophagy induction [, ].This entry represents the C-terminal domain of NRBF2. |
