| Primary Identifier | MGI:2182842 | Allele Type | Spontaneous |
| Gene | Lepr | Strain of Origin | KK |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Sequence analysis of the Lepr gene in the hyperinsulinemic KK mouse strain identified a conservative amino acid substitution; Asp(600)Asn in a highly conserved area of the protein. Data suggests that the variant contributes to the obesity phenotype seen in mice, but that the contribution is only part of a multigenic syndrome. |
