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Publication : Fatty Acid-Induced T Cell Loss Greases Liver Carcinogenesis.

First Author  Shalapour S Year  2016
Journal  Cell Metab Volume  23
Issue  5 Pages  759-61
PubMed ID  27166937 Mgi Jnum  J:235376
Mgi Id  MGI:5796213 Doi  10.1016/j.cmet.2016.04.018
Citation  Shalapour S, et al. (2016) Fatty Acid-Induced T Cell Loss Greases Liver Carcinogenesis. Cell Metab 23(5):759-61
abstractText  A new study has added loss of CD4(+) T cells caused by aberrant lipid metabolism to the list of mechanisms promoting nonalcoholic steatohepatitis progression to liver cancer (Ma et al., 2016). Exposure of CD4(+) T cells to free linoleic acid causes their ROS-mediated depletion, thereby favoring liver cancer growth.
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