First Author | Shalapour S | Year | 2016 |
Journal | Cell Metab | Volume | 23 |
Issue | 5 | Pages | 759-61 |
PubMed ID | 27166937 | Mgi Jnum | J:235376 |
Mgi Id | MGI:5796213 | Doi | 10.1016/j.cmet.2016.04.018 |
Citation | Shalapour S, et al. (2016) Fatty Acid-Induced T Cell Loss Greases Liver Carcinogenesis. Cell Metab 23(5):759-61 |
abstractText | A new study has added loss of CD4(+) T cells caused by aberrant lipid metabolism to the list of mechanisms promoting nonalcoholic steatohepatitis progression to liver cancer (Ma et al., 2016). Exposure of CD4(+) T cells to free linoleic acid causes their ROS-mediated depletion, thereby favoring liver cancer growth. |