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Protein Coding Gene : Adora3 adenosine A3 receptor
Primary Identifier  MGI:104847 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  11542
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables G protein-coupled adenosine receptor activity. Acts upstream of or within several processes, including G protein-coupled adenosine receptor signaling pathway; positive regulation of intracellular signal transduction; and positive regulation of secretion. Located in plasma membrane. Is active in neuromuscular junction. Is expressed in aorta; forebrain; heart; spleen red pulp; and testis. Orthologous to human ADORA3 (adenosine A3 receptor).
PHENOTYPE: Mice homozygous for targeted mutations that inactivate the gene are phenotypically indistinguishable from wild-type mice. [provided by MGI curators]
  • synonyms:
  • Gpcr 2,
  • MGD-MRK-16343,
  • RIKEN cDNA 1700001D09 gene,
  • 1700001D09Rik,
  • Gpcr2,
  • ARA3,
  • MGD-MRK-28143,
  • RIKEN cDNA 4930578J19 gene,
  • G-protein coupled receptor 2,
  • A3R,
  • MGI:1923096,
  • Adora3,
  • 4930578J19Rik,
  • MGI:1916546,
  • AA3R,
  • MGI:99563,
  • adenosine A3 receptor,
  • A3AR
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

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2 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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