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Allele : Spi1<tm1.1Dgt> Spi-1 proto-oncogene; targeted mutation 1.1, Daniel G Tenen
Primary Identifier  MGI:3045207 Allele Type  Targeted
Attribute String  Hypomorph Gene  Spi1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Sfpi1tm1Dgt mice were crossed with mice carrying Tg(CMV-cre)1Cgn. Activity of the cre recombinase resulted in excision of the upstream regulatory element producing a hypomorphic allele. Mice homozygous for this allele produced only about 20% of wild-type protein product.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Sfpi1<kd/kd>,
  • PU.1<kd/kd>,
  • PU.1<kd/kd>,
  • deltaUREneo,
  • deltaUREneo,
  • Sfpi1-knockdown,
  • Sfpi1-knockdown,
  • PU.1-knockdown,
  • (frt-PGKneo-frt----loxp),
  • UREdeltaneo,
  • PU.1-knockdown,
  • (frt-PGKneo-frt----loxp),
  • UREdeltaneo,
  • Sfpi1<kd/kd>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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9 Publication categories

Trail: Allele




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