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Protein Coding Gene : Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif 9

Primary Identifier  MGI:1916320 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  101401
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables endopeptidase activity. Involved in several processes, including circulatory system development; negative regulation of endothelial cell migration; and negative regulation of sprouting angiogenesis. Acts upstream of or within several processes, including camera-type eye development; positive regulation of melanocyte differentiation; and response to bacterium. Located in cell surface and extracellular space. Is expressed in several structures, including alimentary system; embryo mesenchyme; endocrine gland; eye; and genitourinary system. Orthologous to human ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9).
PHENOTYPE: Homozygous null mice display embryonic lethality before somite formation. Mice heterozygous for a knock-out or ENU-induced allele exhibit a ring of epidermal hypopigmentation in the tail. [provided by MGI curators]
  • synonyms:
  • Martin Hrabe de Angelis undefined mutation 4,
  • ADAM metallopeptidase with thrombospondin type 1 motif 9,
  • gsf undefined 3,
  • MGI:3530326,
  • 1810011L16Rik,
  • RIKEN cDNA 1810011L16 gene,
  • RIKEN cDNA 8430403M15 gene,
  • MGI:2442011,
  • MGI:5629510,
  • UND3,
  • 8430403M15Rik,
  • Martin Hrabe de Angelis undefined 3,
  • expressed sequence AW743315,
  • AW743315,
  • Mhdaund4,
  • UND4,
  • RIKEN cDNA E030027K14 gene,
  • Mhdaund3,
  • E030027K14Rik,
  • Gsfund3,
  • MGI:2141719,
  • Adamts9

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For