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Comment :

Type  MGI:General Description  increased serotonin levels and increased synthesis of the serotonin precursor 5-hydroxytryptophan (5-HTP) after treatment with m-hydroxybenxylhydrazine in the frontal cortex and striatum, compared to mice in a BALB/cJ background that are homozygous for TphArg447 and have an arginine rather than a proline at amino acid residue 447 of Tph2