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Protein Coding Gene : Smtnl1 smoothelin-like 1

Primary Identifier  MGI:1915928 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  68678
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables several functions, including calmodulin binding activity; protein domain specific binding activity; and protein phosphatase 1 binding activity. Involved in negative regulation of DNA-templated transcription and positive regulation of vasoconstriction. Acts upstream of or within several processes, including muscle organ morphogenesis; response to activity; and vasoconstriction. Located in I band; M band; and nucleus. Is expressed in several structures, including aorta; diaphragm; genitourinary system; intestine; and skeletal muscle. Orthologous to human SMTNL1 (smoothelin like 1).
PHENOTYPE: Mice homozygous for a null allele exhibit vascular and muscular adaptations normally found in exercised animals as well as increased exercise endurance. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1110030K22 gene,
  • 1110030K22Rik,
  • Smtnl1,
  • smoothelin-like 1,
  • Chasm

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For