Primary Identifier | MGI:96940 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 17227 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables serine-type endopeptidase activity. Involved in proteolysis. Acts upstream of or within regulation of angiotensin levels in blood. Predicted to be active in cytoplasm; extracellular space; and intracellular membrane-bounded organelle. Is expressed in lower jaw and upper jaw. PHENOTYPE: Homozygous inactivation of this locus affects thrombin regulation and fibronectin turnover. [provided by MGI curators] |