Primary Identifier | MGI:3664575 | Allele Type | Spontaneous |
Gene | Cd4 | Strain of Origin | C57BR/cdJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Sequence analysis revealed that one thymine was substituted for the 14 bp at the junction between exon VIII and intron VIII. This results in the skipping of exon 8 in the expressed transcript, resulting in a deletion of the transmembrane domain and C-terminus of the encoded protein. Soluble Cd4 is detectable in the sera of mutant mice. |