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Allele : Cd4<del> CD4 antigen; deletion

Primary Identifier  MGI:3664575 Allele Type  Spontaneous
Gene  Cd4 Strain of Origin  C57BR/cdJ
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence analysis revealed that one thymine was substituted for the 14 bp at the junction between exon VIII and intron VIII. This results in the skipping of exon 8 in the expressed transcript, resulting in a deletion of the transmembrane domain and C-terminus of the encoded protein. Soluble Cd4 is detectable in the sera of mutant mice.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele