Primary Identifier | MGI:2668345 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Map2k2 |
Transmission | Germline | Strain of Origin | STOCK 129/Sv and C57BL/6J and SJL |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin selection cassette replaced sequences from exons 4, 5, and 6. This results in the loss of kinase subdomains VII and VIII. Western blot analysis of protein extracts from E11.5 embryos indicated that both full length and truncated protein were absent. |