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Allele : Map2k2<tm1Chrn> mitogen-activated protein kinase kinase 2; targeted mutation 1, Jean Charron

Primary Identifier  MGI:2668345 Allele Type  Targeted
Attribute String  Null/knockout Gene  Map2k2
Transmission  Germline Strain of Origin  STOCK 129/Sv and C57BL/6J and SJL
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced sequences from exons 4, 5, and 6. This results in the loss of kinase subdomains VII and VIII. Western blot analysis of protein extracts from E11.5 embryos indicated that both full length and truncated protein were absent.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • MEK2<->,
  • MEK2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

37 Publication categories

Trail: Allele