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Protein Coding Gene : Ppp1r13b protein phosphatase 1, regulatory subunit 13B
Primary Identifier  MGI:1336199 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  21981
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable p53 binding activity. Predicted to be involved in intrinsic apoptotic signaling pathway by p53 class mediator. Predicted to act upstream of or within apoptotic process. Predicted to be located in several cellular components, including cytosol; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including blood; brain; cardiovascular system; embryo mesenchyme; and yolk sac. Orthologous to human PPP1R13B (protein phosphatase 1 regulatory subunit 13B).
PHENOTYPE: Homozygous null mutants show lymphatic vascular phenotypes with subcutaneous edema detected only during embryogenesis, delayed lymphatic vessel formation, and mispatterned collecting lymphatic vessels. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI449786,
  • MGI:2145037,
  • MGI:2144829,
  • AW545810,
  • expressed sequence AW545810,
  • Ppp1r13b,
  • AI449786,
  • ASPP1,
  • protein phosphatase 1, regulatory subunit 13B
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6 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

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